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Most common fast-acting PDE5 drug that lasts in your system for up to 18 hours. If the drug still doesn’t work after several attempts, or if you have questions or concerns about using Cialis, talk with your doctor. Remember, you should not change your dosage of Cialis without your doctor’s recommendation. Talk with your doctor if you have questions or concerns about your current dosage. If you have questions about what your Cialis dosage should be, talk with your doctor. Then they’ll adjust your dosage over time to reach the right amount for you.

Nitric oxide then activates the enzyme, guanylate cyclase, which causes the production of cyclic guanosine monophosphate (cGMP). It is the cGMP that is primarily responsible for the erection by affecting the amount of blood that the blood vessels deliver and remove from the penis. Cialis and Viagra inhibit an enzyme called phosphodiesterase-5 (PDE5) which destroys the cGMP. Thus, Cialis and Viagra prevent the destruction of cGMP and allows cGMP to accumulate and persist longer. The longer cGMP persists, the more prolonged the engorgement of the penis. Studies show that the drug begins to work 30 minutes to 6 hours after you take your first dose.

If you have any symptoms of high blood pressure, such as headaches or chest pain, tell your doctor right away. They’ll help determine what’s causing the increase in blood pressure and the best way to treat it. A decrease in blood pressure may be more likely if you’re taking Cialis along with other medications that can also lower blood pressure. For example, if you take your “as-needed” dose of 20 mg twice a day, you’ll end up taking 40 mg.

Most of these online providers allow you to meet with a licensed doctor in your state virtually. If your insurance company covers brand-name ED medications, they’re very likely to cover generics, too, which will bring down the price even further. These medications are available in various doses and can be taken with or without food. However, taking Viagra after eating a high fat meal does slow the rate of absorption. For erectile dysfunction, take 1 tablet at least 30 minutes before you want to have sex. If you have a private prescription for tadalafil, read the information that comes with your medicine carefully.

These drugs include sildenafil (Female Viagra) and tadalafil (Cialis). Both are approved for treating erectile dysfunction and pulmonary arterial hypertension, a type of high blood pressure that affects the arteries in the lungs and heart. ED severity ranged from mild to severe and BPH severity ranged from moderate to severe. The full study population had a mean age of 63 years (range 45 to 83) and was 93% White, 4% Black, 3% other races